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[4]Patent: US2014/275080,2014,A1 .Location in patent: Paragraph 0407

Naturally produced by most living organisms, peptides are short-chain amino acid molecules that play multiple roles in cellular function, including hormone signalling, immune response, gene expression, and ion transport, to name a few

In 2015, edaravone was approved for ALS treatment in Japan (Okada et al., 2018) and by the Food and Drug Administration of United States in 2017 (Watanabe et al., 2018)