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Alfenito et al, 1998), and naturally occurring endogenous reactive electrophilic compounds (Marrs, 1996), but may have then been recruited to detoxify anthropogenic exogenous xenobiotics (Kreuz et al, 1996

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Consequently, these findings raise important questions regarding the extent to which the effects of GLP-1 receptor agonism and amylin receptor activation may be additive or synergistic across different metabolic phenotypes