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Although it is most commonly observed in the legs , it can also affect the arms in some cases

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Governments and international organizations must collaborate to develop and implement effective laws and regulations to govern the development of AI and ensure the protection of public interests

To achieve quantification and external validation, high-resolution imaging should be paired with mechanical measurements to resolve skin-surface microrelief trajectories and cellECM interaction forces, with standardized QC readouts across barrier function, secretome, and mechanics 131,134