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Mitochondrial dysfunction, oxidative stress, inflammation, and impaired ATP production occur in a feedforward cycle, serving as both consequences and causes of the marked reduction in glucose metabolism in the brain across the spectrum of ADRD development (Wang et al., 2017)

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The data shows that since 2015, the rate of drug overdose deaths among the Black Community have outpaced other groups

Others found that complexes II, III, and V in the temporal cortex and complex I in the frontal cortex were downregulated in ASD subjects [80]