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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.St-Pierre J., Buckingham J.A., Roebuck S.J., Brand M.D

The clinical benefits were greatest in those who took folic acid for more than 12 weeks and those whose homocysteine levels dropped by more than 25%

It works by enhancing insulin secretion, reducing glucagon levels, and slowing gastric emptying, which contributes to appetite suppression and weight reduction