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6 Analysis of Nucleosome Deacetylase Activity for Fluorescein-labeled WT LHC and Y391K LHC

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Although the genetic road to cancer or genome instability is relatively straightforward which occurred by mutation of tumor suppressors and/or oncogenes causes either a loss or gain of function and abnormal expression

The terms "polypeptide," "protein," and "peptide" include compositions of the invention that also include "analogs," or "conservative variants" and "mimetics" or "peptidomimetics" with structures and activity that substantially conespond to the polypeptide from which the variant was derived