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Signs and symptoms of vitamin B12 deficiency can include fatigue, pale skin, headaches, shortness of breath, fast heartbeat, gastrointestinal issues, mouth inflammation, paresthesias (abnormal sensations), decreased cognitive ability, depression, muscle weakness, imbalance and incoordination, vision problems, and erectile dysfunction

doi:10.1177/070674379003500811

Metabolic findings in rodents have a long history of not translating cleanly, so the fat-loss story should be read as promising preclinical data, not an established human outcome

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