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Regulation of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 cells by 2-hydroxy-3-en-anhydroicaritin involves down-regulation of NF-kappaB and MAPK expression

However, no combination studies have been conducted, and the interaction between telomerase activation and sirtuin-mediated pathways is complex -- SIRT1, for example, can influence telomere biology through effects on shelterin complex proteins

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