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You can be cynical about that, of course

Issara-Amphorn J, Surawut S, Worasilchai N et al (2018) The synergy of endotoxin and (13)--d-glucan, from gut translocation, worsens sepsis severity in a lupus model of Fc gamma receptor IIb-deficient mice

Moving release farther down the intestinal tract changes the pH, enzymes, transit conditions, mucus layer, surface area, and local concentration around the formulation

For diagnostic purposes, PET and SPECT tracers require radionuclide labels, emitting positrons and gamma rays respectively, with half-lives matching the biological half-life of the targeting vector