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Front Cell Neurosci 12:338 Ardah MT, Paleologou KE, Lv G, Menon SA, Khair SBA, Lu J-H, Safieh-Garabedian B, Al-Hayani AA, Eliezer D, Li M (2015) Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils

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Finally, dose-controlled clinical trials of pathway modulators such as metformin, alongside biomarker-guided imaging of autophagic flux, are warranted to translate these promising pre-clinical findings into neuro-restorative strategies for patients with SCI