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Given that HT-22 cells were treated with high-glucose prior to co-culture with NSCs, the neurospheres themselves were not directly exposed to high glucose, and similarly, differentiating immature neurons were not directly exposed to either high glucose or RGMa

It binds and activates GHRH receptors on pituitary somatotrophs, directly stimulating growth hormone synthesis and pulsatile release the same signaling axis as endogenous GHRH, but massively extended

Despite hundreds of thousands of individuals receiving spinal fusion surgery annually, there are various factors that bring into question the clinical significance and efficacy of the procedure

NF-B signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration