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Common measures include growth hormone (GH) levels, insulin-like growth factor-1 (IGF-1) levels, lean body mass, body composition, muscle fiber size and markers of muscle protein synthesis

Whether NMDA-R hypofunction as a specific mechanism accounts for any important component of the illness is still not evident

They believe tissue levels of those factors are probably far lower

This article reviews the common forms of PCD involved in the pathogenesis of DOR, including apoptosis, autophagy, ferroptosis, pyroptosis, and necroptosis (Figure 1)