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Acknowledgments Financial support from FCT/MCTES through national funds UID/MULTI/04378/2019 and Norte Portugal Regional Coordination and Development Commission (CCDR-N)/NORTE2020/Portugal 2020 (Norte-01-0145-FEDER-000024) and a PhD grant (SRRH/BD/139622/2018) attributed to D

Most current therapeutic candidates for NDDs face challenges in crossing the bloodbrain barrier, substantially limiting their clinical efficacy (Ross and Poirier, 2004)

However, if there are already existing deeply set age spots, you need to be consistent to witness gradual results

So if you can do something to recreate the possibility of your growth hormone release, which we know comes from the brain but also comes endogenously from cells which is a whole other topicbut if you can do it in a physiologic (meaning a normal fashion that the body is accustomed to, meaning not exogenously, meaning giving growth hormone synthetically)