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Autism spectrum disorders and autistic traits: A decade of new twin studies

Mice lacking CYP27B1 or VDR exhibit thymic atrophy, reduced AIRE + mTECs, impaired T cell negative selection, and gene expression profiles resembling those of aged thymic tissue [143]

It should be noted though, that inappropriate administration of folate when there is a vitamin B12 deficiency may cause neurologic and hematologic relapse (Reynolds, 2014)