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These enzymes are involved in methylation and acetylation and depend on metabolites as cofactors, integrating the epigenome and transcriptome

[383] showed that ferulic acid administered orally one hour after the UC induction and during five days at 20, 40, and 60 mg/kg doses ameliorated UC through the inhibition of the LPS-TLR4-NF-B and NF-B-INOS-NO signaling pathways