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Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway

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SARS-CoV-2, the virus responsible for the 2020 COVID-19 pandemic (103), belongs to the genus Betacoronavirus and subgenus Sarbecovirus and, due to its similar receptor-binding domain, it is assumed, similarly to SARS-CoV, to infect type II pneumocytes entering via the angiotensin-converting enzyme II receptor (104)

It was found that mice that had normal plasma Hcy at the start of the study, that were fed Met-rich diets exhibited atheromatous effects, while mice with normal Met levels were deficient in vitamin B and developed severe hyperhomocysteinemia (221)