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Anti-Cancer Drugs (2007) 18(4):389404

However, with the emergence of a body of data documenting differences in autistic brains that were most likely of physiological originparticularly neuropathological identification of neural and glial inflammation associated with enlargement of the areas of the brain, including cerebrum, that continue to grow and mature postnatallythe assumption of congenital origin came under question, since the processes of generating such changes are often associated with environmental etiologies including oxidative stress and neuroinflammation generated by noxious environmental exposures, including activation of glial cells [46, 271, 315, 377, 411, 522, 548]

Jastreboff AM, Kaplan LM, Frias JP, Wu Q, Du Y, Gurbuz S, et al

Multiple signaling molecules regulate cardiovascular energy metabolism, playing key roles in the transcription of metabolism-related genes, including AMPK, PGC-1, SIRT, and PPARs