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Upon stimulation, the inflammasome receptors oligomerize and recruit pro-caspase 1 via ASC, thereby stimulating pro-caspase 1 processing and conversion to active caspase 1

Immunocytochemistry and immunohistochemistry Glioblastoma patient specimens were obtained and analyzed in accordance with an Institutional Review Board-approved project plan (Kantonale Ethikkommission Zrich, Switzerland, KEK-ZH-Nr./BASCE-Nr