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Vilar L, Vilar CF, Lyra R, Freitas MDC

5-Fluorouracil neurotoxicity in a patient with normal dihydropyrimidine dehydrogenase activity

Although its specific effectiveness for ASD is not well established, ginsengs potential to improve mental performance and synaptic plasticity and alleviate symptoms of anxiety and depression could benefit individuals with ASD [136]

On one hand, its multi-target therapeutic potential lacks validation through large-scale, randomized, double-blind, placebo-controlled clinical trials in humans, which hinders the effective translation of preclinical findings into clinical applications