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Odevixibat, a small molecule that inhibits ileal resorption of BAs belonging to the class of ileal BAs transporter (IBAT) inhibitors, was the first drug approved for the treatment of PFIC patients 6 months old due to its efficacy on both pruritus and reduction of serum BAs as well as its good tolerability in 2021 [16]

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Many of these vitamins may also upset the digestive tract and can only be taken in small doses orally, limiting the amount of vitamins available for absorption

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