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Compounded peptides are sometimes offered when branded medications are expensive or in short supply, but the FDA has warned that compounded semaglutide and tirzepatide may not meet the same safety or quality standards as FDA-approved products (FDA statement on compounded semaglutide)

Additionally, section 1834A(b)(3) of the Act, implemented at 414.507(d), provides for a phase-in of payment reductions, limiting the amounts the CLFS rates for each CDLT (that is not a new advanced diagnostic laboratory test (ADLT) or new CDLT) can be reduced as compared to the payment rates for the preceding year

doi: 10.1016/j.cjca.2019.08.001

Jelovac N, Sikiric P, Rucman R, Petek M, Marovic A, Perovic D, et al