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These findings confirm that CRGs and DRGs have the potential to alter the TME and enhance treatment responsiveness, offering critical strategies for personalized precision medicine (Hu et al., 2023

Semin Liver Dis 43:418428

For example, increased level of galectin-3-binding protein (responsible for cancer development, progression and metastasis) inflammatory markers (IFN-, IFN-, IFN-, TNF-), trombospondin-1(increased in tumors and associated with thrombosis), -1-acid glycoprotein-2 (associated with demyelinating diseases), and reduced levels of long palate, lung and nasal epithelium carcinoma-associated protein 1, lactotransferrin, adiponectin and -1-acid glycoprotein-1 may be the result of immunosuppression similar to that of sepsis