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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Transduction of MDR1 into human and mouse hematopoietic progenitor cells: Use of Rhodamine (Rh123) to determine transduction frequency

Protocol [1] A total of two sets of adult male C57BL/6j mice weighing 21-26 g are randomly assigned to one of four groups and treated with intraperitoneal (i.p.) delivery of (i) vehicle (50 L isotonic saline/5% ethanol), (ii) melatonin (4 mg/kg, dissolved in 0.9% isotonic saline/5% ethanol), (iii) Wortmannin, and (iv) melatonin/Wortmannin immediately after reperfusion

The dominant, although transient, effect of physical exercise was observed only in case of albumin and total protein concentrations in the blood these parameters increased after exercise