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To address this issue, cell membrane-derived nanovesicles were developed to as a new kind of lymph node targeting nanocarriers

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In the absence of T-bet, there was an enhancement of the Th2 immune response, characterized by an increased production of activated GATA-3 + CD4 + T cells and elevated levels of eosinophil chemokines, as well as MCP-1 and G-CSF cytokines ( The expression of T-bet in Treg is essential for mitigating Th1-mediated immunopathology during Toxoplasma gondii infection in murine models ( de novo differentiation of Tregs into T-bet + Tregs