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Nat Commun 14 , 5709 (2023)

Renaud J, Bassareo V, Beaulieu J, Pinna A, Schlich M, Lavoie C, et al

Glutathione was shown to regulate the redox status of cells

By converting APAP into water-soluble forms, this phase II pathway helps detoxify and eliminate APAP from the body, reducing the risk of metabolite accumulation and potential harm