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Description

Other drugs with alcohol groups may be metabolized in a similar way as long as steric hindrance does not prevent the alcohol from reaching the active site

- 4% :420

Nature 636 , 737744 (2024)

In the first step, apo(a) binds non-covalently to lysine-rich regions in apoB-100 that reside on LDL particles through structural elements of the unique K IV 58, the lysine-binding sites of which are cognate to the lysine-coordinating residues of apoB