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The most common, VEGF-A, has some isoforms that are mainly soluble and other which are mainly matrix-bound, and Chen et al

To our knowledge, this is the first intervention to specifically target microglial lipid-metabolic dysfunction evoked by butyrate depletion, providing pre-clinical proof-of-concept for repurposing butyrate against MPs-triggered neurotoxicity and broadening its therapeutic scope in neurodegenerative diseases