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Studies have shown that the expression level of GPER in patients with T2D is closely related to their insulin sensitivity, with the downregulation of GPER expression being directly associated with the occurrence of insulin resistance [137]

Panza, F

This study found that subjects who received Myers Cocktail once a week for 8 weeks experienced some relief from fibromylagia though the results were not statistically significant

EE activated IGF-1 signal pathway through IGF-1R To examine the activation of key components of IGF-1 signal pathway, phosphorylation of AKT, P70S6K, and ERK was studied by western blot after EE, IGF-1, and testosterone treatment (Fig