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It can also reverse the negative effects caused by BRIP1 downregulation, leading to a decrease in MDA levels and intracellular Fe 2+ content and an increase in GSH, Gpx4, and SLC7A11 levels ( 2+ and MDA levels, and reduced M2-type macrophage infiltration, whereas Fer-1 reversed these conditions ( Ferroptosis inducer 56 (FIN56) is a ferroptosis inducer that inhibits the activity of GPX4, thus leading to the accumulation of lipid peroxides within cells and thereby inducing ferroptosis

NADPH, generated through glutamine metabolism, supports glutathione regeneration, helping keep ROS levels in check

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Due to its selective effect on cancer cells, S-Acetyl-L-glutathione shows promise as a potential new inducer of lymphoma cell apoptosis and may have clinical value for lymphoma patients