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Together, our observations that a small molecule NNMT inhibitor can increase NAD + and SAM concentrations in differentiated adipocytes and reduce adiposity in DIO mice, suggest that treatment with an NNMT inhibitor effectively reverses obesity via modulation of the NAD + salvage and SAM-mediated (e.g., polyamine flux) pathways to regulate energy expenditure in the adipose tissue

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Nerve problems may include numbness, pins and needles, vision changes and unsteadiness

It helps to maintain proper nervous system function and is also involved in energy production and lowering Homocysteine levels (which reduces the risk of heart disease and stroke)