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39 Of note, the authors did treat the patient with ursodeoxycholic acid 600 mg/day for close to a year

Recent studies have shown that abiraterone acetate (Zytiga), an inhibitor of the cytochrome P450 enzyme CYP17, impedes androgen synthesis and thus lowers the level of circulating ligand, improving overall survival in well-powered, randomized phase III studies 163,164