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Increased amounts of reactive oxygen species (ROS) in cancer cells may facilitate tumour development, genetic instability, and resistance to programmed cell death (apoptosis) [11, 94, 95]

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Indeed, vitamin E prevents de novo membrane oxidative damage, folate maintains levels of the endogenous antioxidant GSH and ALC prevents A-beta-induced mitochondrial damage and ATP depletion providing superior protection to that derived from each agent alone [151]

In vivo hemostasis test A mouse tail amputation model and a mouse hemorrhagic liver model were used to evaluate the hemostatic effect of the GEK hydrogel