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250 Therefore, targeting dyslipidemia and its downstream effects may offer promising therapeutic avenues for DPN management (Fig

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Among them, dislipidaemia is a well-known risk factor whose control has proven to reduce Cardiovascular morbimortality.34 While there is a large therapeutic armamentarium for dyslipidaemia the level of control over lipid abnormalities is clearly suboptimal, particularly in patients with a (very) high cardiovascular risk, where reducing absolute risk is crucial.58 An update of ESC Guidelines on Cardiovascular Disease Prevention in Clinical Practice was recently published.9 These guidelines are supported by the major Spanish scientific societies involved in cardiovascular disease, including the CEIPV (Comit Espaol Interdisciplinario de Prevencin Vascular).1013 Therapeutic targets have been established and widely accepted for lipid-lowering therapies

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