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Moreover, amino acids like glycine, cysteine, glutamine, methionine, taurine, glutamic acid, and aspartic acid are the important ingredients in the function of Phase 2

doi: 10.1186/s40814-023-01235-z 96 GuinaneC

Notably, in RagA/B double-knockout cardiomyocytes that show impaired lysosomal function, phosphorylation of mTORC1 substrates, such as 4E-BP1, is not significantly affected (Kim et al., 2014)

As the only bifunctional enzyme in the ARS family, EPRS activates the WNT/GSK-3/-catenin signaling pathway and stimulates the accumulation of -catenin in the nucleus by directly binding to SCYL2 (SCY1-like protein 2), promoting cancer cell proliferation