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To address the interplay between ROS and antioxidants in cancer chemoresistance, novel therapeutic strategies aim to manipulate redox homeostasis to enhance chemotherapy efficacy

10.1016/j.bbagen.2018.06.003 18 BianJ.CaiF.ChenH.TangZ.XiK.TangJ.et al (2021)

Beck and colleagues reported in 2014 that the 117-patient proof-of-concept study found ipamorelin well tolerated but did not reach statistical significance on its primary composite gastrointestinal endpoint at the studied dose