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doi: 10.1200/JCO.2008.20.6771 3 LoprinziCLQinRDakhilSRFehrenbacherLFlynnKAAthertonPet al

Effects of aerobic exercise on urinary estrogens and progestagens in pre and postmenopausal women

Plant Physiol 129:14731481

The heart-rate cost is mostly the glucagon arm: GLP-1 on its own nudges heart rate up a little and then flattens, while glucagon carries the part that keeps climbing with the dose