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For reaction mixture I, we used the reagent A: 0.64-mM solution of the reduced form of glutathione (GSH) in a mixture of 0.1-M Tris-HCl buffer (pH 8.5) containing 0.34-mM EDTA and an aqueous solution of NaN 3 (26 mg/ml)

Concomitant suppression of NLR family pyrin domain-containing 3 ( NLRP3 ), interleukin 6 ( IL6 ), and inhibin subunit Beta B ( INHBB ) specifically in M9a+sh EPAS1 versus M9a+shCTR indicated attenuated inflammation, while transcriptomic profiles showed no divergence between M9a+shCTR and M7/8+shCTR (Fig

Gimbrone is a member of the National Academy of Sciences, the American Academy of Arts and Sciences, and the Institute of Medicine

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