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Biofactors 48, 521551

M., Forman-Kay, J

JXY extract inhibited the expression and transcriptional activity of -catenin protein, while also suppressing target proteins of the Wnt/-catenin pathway, such as c-Myc and Cyclin D ( Beyond the Wnt/-catenin signaling pathway, accumulating evidence indicates that formulations and bioactive metabolites derived from TCM can effectively ameliorate CRC pathogenesis through multi-target modulation of critical signaling pathways