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The S-glutathionylation is a process in which the interaction between GSSG and cysteinyl residues of proteins results in the formation of mixed disulfides (22)

178,179,180,181,182 Given that DNA damage-activated PARPs account for up to 90% of cellular NAD + consumption, the DNA repair activity is highly dependent on the cellular NAD + concentration

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Hyperthermia is usually combined with chemotherapy or radiotherapy to treat advanced and recurrent cancers (Owusu 2013