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Neuroprotective effects of Diallyl Trisulfide in Sod1-G93a transgenic mouse model of amyotrophic lateral sclerosis

The mitochondrial activity, glutathione-S-transferase, GSH levels, and MnSOD levels in the brain are decreased and increase in levels of 4-hydroxynoneal (HNA), thiobarbituric acid reactive substances (TBARS), malondialdehyde (MDA) and increase in levels of protein carbonyl groups [35, 36, 37, 38], which causes increase the oxidative stress in the brain cells and further led to cause cell damage

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It is potentially harmful