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The epidemiology and pathology of BPD have changed over the past 50 years

Antimicrob Agents Chemother 58(5):25202527

In a subsequent study using NFE2L2/PGC1 double knockout (dKO) mice model, they observed upregulation of autophagy markers PINK1 and PARKIN together with damaged mitochondria, with no increase in the colocalization of lysosomal marker (LAMP2) and mitochondrial marker (ATP synthase ), suggesting an inability of the autophagosome to fuse with the lysosome (Sridevi Gurubaran et al., 2020)