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Deficiency of Atg7 (Autophagy related 7 protein) resulted in heightened glycolytic activity but impaired mitochondrial respiration, reduced ATP production as well as lipid droplet accumulation in neutrophil progenitor cells, indicating that during neutrophil development autophagy supports a metabolic shift from glycolysis to FAO and mitochondrial respiration (Riffelmacher et al., 2017)

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Assi R, Boddu P, Kadia TM, Estrov ZE, Garcia-Manero G, Ravandi F, Jabbour EJ, Takahashi K, Konopleva MY, Andreeff M, Zahr AA, DiNardo CD, Borthakur G , Jain N, Pemmaraju N, Yilmaz ME, Short N, Ning J, Pierce SA, Wierda WG, Cortes JE, Kantarjian H, Daver NG