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human evidence is still emerging.) Musculoskeletal injury or post-surgical recovery Chronic tendonitis, ligament sprains, or joint pain Athletes or active individuals with overuse injuries Patients with GI inflammation or ulcerative symptoms Individuals seeking regenerative or anti-inflammatory support Generally well-tolerated in available data, but may include: Mild redness or irritation at injection site Transient headache, nausea, or dizziness (rare) Potential for allergic reaction (rare) Not FDA-approved

Mechanistically, p53 suppresses the production of NADPH by inhibiting malic enzymes and G6PD, as well as the associated pentose phosphate pathway

[7] Within days, corneocyte cohesion decreases and comedonal plugs are extruded

doi: 10.1038/s41575-022-00634-6