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Description

Breast cancer and circadian disruption from electric lighting in the modern world

Munroe WP, Rindone JP, Kershner RM

Brodalumab (AMG 827) is a human IgG2 mAb that binds to IL-17 receptor A (IL-17RA), thereby inhibiting IL-17A, IL-17F, and IL17-A/F heterodimer signaling over the IL-17RA/RC complex and IL-17E signaling across the IL-17RA/RB complex