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In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia

Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, Li J, Behrens C, Parra ER, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Kadara H, Scheet P, Roarty E, Ostrin EJ, Wang X, Carter BW, Antonoff MB, Zhang J, Vaporciyan AA, Pass H, Swisher SG , Heymach JV, Lee JJ, Wistuba II, Hong WK, Futreal PA, Su D, Zhang J

During the treatment of CIA rats, we found that the HA-Lipo@G/D treatment group significantly reduced the expression of inflammatory factors IL-6 and TNF- while concurrently upregulating the anti-inflammatory IL-10 level in plasma

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