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Certainly, these therapies are effective, but they most often lead to severe long-term complications such as infections, Secondary malignancy, ovarian failure, disturbances in gastrointestinal tract functionality, miscellaneous hematologic conditions that include leucopenia or anemia, organ damage, and long-term use of corticosteroids may lead to weight gain, delivery of osteoporosis, and diabetes mellitus ( Literature reviews regarding the association of probiotics with lupus indicate that they may have beneficial contributions to immune regulation and inflammation, two pivotal components in lupus pathogenesis

Simultaneously, inflammation can result in oxidative stress (67, 68)

Oosthuyse T, Bosch AN

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