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doi: 10.1093/rpd/ncl431 67 FacoettiAMariottiLBallariniFBertolottiANanoRPasiFet al

4.2 Reduced glucotoxicity and lipotoxicity Glucotoxicity is characterized by irreversible tissue and cell damage resulting from insulin resistance and persistently elevated glucose levels stemming from excessive carbohydrate intake (Mota et al., 2016)