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ARA-290 (cibinetide) is an eleven-amino-acid peptide derived from the helix-B domain of erythropoietin

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Through ubiquitin-dependent or ubiquitin-independent receptor-mediated pathways, damaged mitochondria are enclosed in autophagosomes and transported to lysosomes for degradation and recycling, which is important for basal mitochondrial turnover and the maintenance of physiological conditions [2, 3] (Fig