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While NAC effectively replenishes GSH in GSH-deficient conditions, its ability to increase GSH levels under normal conditions is generally limited (Nazrolu et al., 2013

Similarly, hsa-miR-532-3p enhances the antioxidant capacity of human decidual mesenchymal stem cells (hDMSCs) by activating the Nrf2 signaling pathway through targeting Keap1, thereby reducing the embryonic resorption rate in recurrent spontaneous abortion (RSA) [177]

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[72] The description of protein folding by the leveling free-energy landscape is also consistent with the 2nd law of thermodynamics