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Semin Oncol 29(1 Suppl 4):95-101, 2002

A logical explanation behind this observation comes from the fact that elongation of the polymeric fibrillar structure of -synuclein requires a constant supply of free protons from the solution in order to mask the C terminal negative charges and prevent the interference of the N and C terminal association during fibrillation

Components of an antigen called epitopes are the regions where the antigen and the antibody connect on the pathogenic cell, a bit like a space docking station